中国遗传资源保护与疾病防控教育部重点实验室 English
   

说明: C:\Users\Y\Desktop\IMG_20170406_101738.jpgYantao Bao

Institution

Guangdong Key Laboratory of  Genome Instability and Human Disease Prevention, Department of Biochemistry  and Molecular Biology, School of Medicine, Shenzhen University

Position

Postdoc

E-mail

baoyt@ems.hrbmu.edu.cn

Tel.

+86-17748679829

Address (office)

Building A7, Xili Campus,  Shenzhen University. 1066 Xueyuan Avenue, Nanshan District, Shenzhen, China

 

Education

2012.9-2016.6

Harbin Medical University, China


PhD in Medical Genetics

2007.9-2012.7

Harbin Medical University, China


BS in Basic Medical Science


Employment

2016.8-present

Postdoc

College of Basic Medical Science, Health Science Center

Shenzhen University


Research Interest

——Molecular mechanisms involved in the generation of genome instability.

——The implications of DNA damage response in cancer progress.

——Biological functions of amplified genes in cancer cells.

Publications

1. Bao Y, Liu J, You J, Wu D, Yu Y, Liu C, Wang L, Wang F, Xu L, Wang L, Wang N, Tian X, Wang F, Liang H, Gao Y, Cui X, Ji G, Bai J, Yu J, Meng X, Jin Y, Sun W,Guan XY, Zhang C, Fu S. Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts. Oncotarget. 2016 Aug30;7(35):56664-56675. doi: 10.18632/oncotarget.10994. PubMed PMID: 27494853;PubMed Central PMCID: PMC5302943.


2. You J, Liu J, Bao Y, Wang L, Yu Y, Wang L, Wu D, Liu C, Wang N, Wang F, Wang F, Xu L, Tian X, Liang H, Gao Y, Guan R, Bai J, Meng X, Sun W, Guan XY, Zhang C, Fu S, Jin Y. SEI1 induces genomic instability by inhibiting DNA damage response in ovarian cancer. Cancer Lett. 2017 Jan 28;385:271-279. doi:10.1016/j.canlet.2016.09.032. Epub 2016 Oct 3. PubMed PMID: 27697611.


3. Tian X, Liu C, Wang X, Wang F, Wang L, Xu L, Ma J, Gao Y, Bao Y, Wang F, Sun L, Wei J, Lin C, Zhang H, Zhu G, Guan X, Fu S, Zhang C. Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts. Cell Death Dis.  2018 Mar 1;9(3):341. doi: 10.1038/s41419-018-0362-y. PubMed PMID: 29497033; PubMed Central PMCID: PMC5832785.


 

[返回]


Copyright2013© 哈尔滨医科大学遗传学研究室. 版权所有
哈尔滨市南岗区保健路157号
电话: 86-451-86674798  传真: 86-451-86677243  邮箱: hmugenetics@ems.hrbmu.edu.cn